alpha5beta1 integrin induces the expression of non-cartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers
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چکیده
alpha5beta1 integrin induces the expression of non-cartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers Arthritis Research & Therapy 2013, 15:R127 doi:10.1186/ar4307 Nobuho Tanaka ([email protected]) Yasuko Ikeda ([email protected]) Tetsuo Yamaguchi ([email protected]) Hiroshi Furukawa ([email protected]) Hiroyuki Mitomi ([email protected]) Takumi Nakagawa ([email protected]) Shigeto Tohma ([email protected]) Naoshi Fukui ([email protected])
منابع مشابه
α5β1 integrin induces the expression of noncartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers
INTRODUCTION Articular chondrocytes undergo an obvious phenotypic change when cultured in monolayers. During this change, or dedifferentiation, the expression of type I and type III procollagen is induced where normal chondrocytes express little type I and type III procollagen. In this study, we attempted to determine the mechanism(s) for the induction of such procollagen expression in dediffer...
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